Certain influenza virus strains are developing increasing drug resistance and greater ability to spread, a new study warns.
American and Canadian researchers confirmed that resistance to the two approved classes of antiviral drugs can occur in several ways and said this dual resistance has been on the rise over the past three years.
The team analyzed 28 seasonal H1N1 influenza viruses that were present in five countries from 2008 to 2010 and were resistant to both M2 blockers (adamantanes) and neuraminidase inhibitors (NAIs), including oseltamivir and zanamivir.
The researchers found that additional antiviral resistance can rapidly develop in a previously single-resistant influenza virus through mutation, drug response, or gene exchange with another virus.
The study also found that the proportion of tested viruses with dual resistance increased from 00.6 percent in 2007-08 to 1.5 percent in 2008-09 and 28 percent in 2009-10. HealthDay News
American and Canadian researchers confirmed that resistance to the two approved classes of antiviral drugs can occur in several ways and said this dual resistance has been on the rise over the past three years.
The team analyzed 28 seasonal H1N1 influenza viruses that were present in five countries from 2008 to 2010 and were resistant to both M2 blockers (adamantanes) and neuraminidase inhibitors (NAIs), including oseltamivir and zanamivir.
The researchers found that additional antiviral resistance can rapidly develop in a previously single-resistant influenza virus through mutation, drug response, or gene exchange with another virus.
The study also found that the proportion of tested viruses with dual resistance increased from 00.6 percent in 2007-08 to 1.5 percent in 2008-09 and 28 percent in 2009-10. HealthDay News
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